An inferno has left a vacant home a total loss near 12th & D Streets early Friday morning. Lincoln Fire and Rescue said firefighters responded to the home on reports of an odor and found the entire third floor of the home on fire.

Crews attacked the fire from the ground and were eventually able to get ladders up to the roof to put water on the flames. They had unique challenges getting to the fire.

"It was a house that had been divided into multiple units. It was three stories. It had large trees in the yard that limited our access to it, a fire escape in the back that would not allow access to us; it had been condemned," Acting Battalion Chief Ron Trouba said.

Investigators and neighbors told Channel 8 Eyewitness News the home was known to be used by transients, and that several transients had been kicked out of the property last Wednesday. They had a space heater in their possession when they left, possibly using it to keep warm.

It's unknown if any transients returned to the home later, and the building was empty when fire crews finally entered it.

The home was purchased over a year ago with plans to restore it to its original condition.

Despite the fire being contained to the third floor, investigators may never know what actually started the blaze.

"Because that third floor was completely burnt out it may be difficult for them to ever really determine the exact cause of this fire because it's unsafe for the investigators to be up in there," said Nancy Crist of Lincoln Fire and Rescue.

No injuries were reported.